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Wellbutrin XL®: At first, 150 mg once a day in the morning. The only easy method is to reputable the point of view of many thousands of various other consumers Taking more than the recommended dose of bupropion may increase your risk of having a seizure. Webmd. Gov/drugs/postmarket-drug-safety-information-patients-and-providers/ Data submitted by Actavis, Inc. Fda. You’ve been receiving Requip Xl Sale 300 mg per day of another bupropion product for at least 2 weeks, and you require a higher dosage of bupropion, at least 450 mg per day. The usual adult target dose for bupropion hydrochloride extended-release tablets, USP (SR) is 300 mg per day, given as 150 mg twice daily. May 24, 2016 · Bupropion hydrochloride extended-release tablets, USP (SR) may be taken with or without food. …. Feb 08, 2017 · The usual adult target dose for BUDEPRION XL™ (bupropion hydrochloride extended-release tablets) is 300 mg/day, given once daily in the morning. 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